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CD16 抗体

This anti-CD16 antibody is a 小鼠单克隆 antibody detecting CD16 in FACS, IP, WB 和 Func. Suitable for 人.

产品编号 ABIN120566

发货至: 中国

Quick Overview for CD16 抗体 (ABIN120566)

抗原

See all CD16 抗体

CD16

适用

160
44
20
20
20
13
9
8
8
8
3
3
2
2
2
2
2
2
2
2
2
2

人

宿主

小鼠

克隆类型

单克隆

标记

This CD16 antibody is un-conjugated

应用范围

169
36
36
35
29
24
23
15
15
9
6
5
4
2
2
2
2
1
1
1
1

Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Functional Studies (Func)

克隆位点

MEM-154

Discover our top product CD16 Primary Antibody

特异性

The antibody reacts with with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). The antibody MEM-154 recognizes a polymorphism of CD16a (NK cells form), it reacts well with granulocyte form (CD16b) of all subjects.

纯化方法

Affinity Chromatography on Protein-A

免疫原

Human granulocytes

亚型

IgG1
anti-CD16 (CD16) antibody
CD16 适用: 人, Non-Human Primate FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 3G8 unconjugated

anti-CD16 (CD16) antibody
CD16 适用: 人, Non-Human Primate FACS, IP 宿主: 小鼠 Monoclonal LNK16 unconjugated

anti-CD16 (CD16) antibody (FITC)
CD16 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal LNK16 FITC

anti-CD16 (CD16) antibody
CD16 适用: 人, Pig, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MEM-168 unconjugated

anti-CD16 (CD16) antibody
CD16 适用: 人 FACS, IP, WB 宿主: 小鼠 Monoclonal MEM-154 unconjugated

anti-CD16 (CD16) antibody
CD16 适用: 人 FACS, IP, WB, Func 宿主: 小鼠 Monoclonal MEM-154 unconjugated

anti-CD16 (CD16) antibody (Biotin)
CD16 适用: 人 FACS, IP, WB 宿主: 小鼠 Monoclonal MEM-154 Biotin

anti-CD16 (CD16) (AA 17-208) antibody
CD16 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2G10A9 unconjugated

anti-CD16 (CD16) antibody
CD16 适用: 人, Non-Human Primate FACS, IP, Func, IHC (fro) 宿主: 小鼠 Monoclonal 3G8 unconjugated

anti-CD16 (CD16) antibody
CD16 适用: 人, Pig, 绵羊, Cow, 马 FACS, Func 宿主: 小鼠 Monoclonal KD1 unconjugated

应用备注

Flow Cytometry: Recommended dilution: 5-10 m g/mL. Positive control: PBL (peripheral blood lymphocytes) Immunoprecipitation. Western Blotting (non reducing conditions). Functional Application (The antibody blocks binding of human IgG to FcgammaRIII).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

TBS, pH ~8.0 containing 15 mM Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store the antibody at 2-8 °C for up to one month or at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

有效期

12 months
抗原

CD16

别名

CD16

背景

CD16 (FcgRIII) is a 50-80 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

基因ID

2214

UniProt

P08637

途径

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process

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